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Path of Exile 2 – All Permanent Buffs in Act 4 & Interlude

September 10, 2025


Valencia
Latest posts by Valencia (see all)

    What Are Permanent Buffs?

     

    PoE 2 Act 4 & Interlude – Full Permanent Buff Guide

     

    These are lasting bonuses—like Attribute increases, stat boosts, Orbs, skill points, or resistances—tied to campaign events, optional bosses, or quests in Act 4 and Interlude (mini-acts). Once obtained, they persist through your character’s journey.


    Act 4 Permanent Buffs

    Location / Event Reward
    Isle of Kin – Blind Beast +2 Weapon Set Skill Points for defeating the boss.
    Halls of the Dead – Trial Choose one: +5% Fire Res or +5 Strength, +5% Cold Res or +5 Dexterity, +5% Lightning Res or +5 Int.
    Halls of the Dead – Mana +5% Maximum Mana for completing a secondary trial.
    Trail of the Ancestors +2 Weapon Set Skill Points after the trial and speaking to Hinekora.
    Abandoned Prison Choose either +30% Life Recovery or +30% Mana Recovery from Flasks.
    Whakapanu Island – Crab Cave Get a Level 4 Uncut Support Gem.
    Singing Caverns – Beckoning Clam Return the Pearl to NPC Rog to receive a rare Pearlescent Amulet with elemental resistance bonuses.
    Arastas – Morning Bell 3 Regal Orbs when slotted during morning.
    Arastas – Evening Bell 3 Exalted Orbs when slotted during evening.
    Additional Note A logbook unlocks when you collect four map fragments across islands.

    Interlude (Acts 5.x) Permanent Buffs

    Act 5.1 – Ogham

    • Wolvenhold Boss Victory: +2 Weapon Set Skill Points.

    Act 5.2 – Khari Bazaar

    • Molten One’s Gift (Skullmaw Stairway): +5% Maximum Life.

    • Slaying Worm & Scorpion: +2 Weapon Set Skill Points awarded by Risu.

    • Qimah’s Boon Selection: Choose one buff among seven, e.g., elemental resistances, attributes, cooldown speed—this choice can be changed later.

    • Sel Khari Sanctuary: Use two special items on pedestals to receive a Rare Ring, Amulet, or Jewel—like a “wish” for jewelry.

    • Qimah Reservoir Wells: Restoring each well grants a useful currency item.

    Act 5.3 – Mount Kriar

    • Ancient Monument (Ashen Forest): Obtain an Uncut Skill Gem (Level 14).

    • Lythara at Kriar Village: Kill her to gain +40 Maximum Spirit.

    • Yeti in Howling Caves: Defeat it for +2 Weapon Set Skill Points.

    • Elder Madox in Kriar Peaks: Choose a Unique Item reward.

    • Completing the entire Interlude: Grants an extra +2 Weapon Set Skill Points.


    Quick Summary Table

    Region Notable Permanent Buffs
    Act 4 Skill Points, Mana, Flask Recovery, Resistances, Orb rewards
    Interlude – Ogham Weapon Set Skill Points
    Interlude – Khari Life boost, Skill Points, Boons, Jewelry upgrades, Currency
    Interlude – Kriar Skill Gems, Spirit, Skill Points, Unique Item

    GladiatorBoost Spotlight

    Want help making the right choices or optimizing your buff path? GladiatorBoost’s PoE2 Boosting services can guide your campaign run, help you plan choices, and ensure you collect every powerful permanent buff effectively—no effort wasted.